KLOW Blend is a research-use-only reference material combining four well-characterized research peptides — GHK-Cu (copper tripeptide-1), BPC-157 (a gastric-derived pentadecapeptide), TB-500 (an N-acetylated thymosin beta-4 fragment, Ac-LKKTETQ), and KPV (an alpha-MSH-derived tripeptide). As a blend it has no single CAS number, molecular formula, or molecular weight; each component is identified by its own analytical identity. The catalog strength refers to 80 mg total peptide content. It is supplied as a lyophilized powder for in-vitro and analytical research applications only and is not for human or animal use.
Component identities
The blend comprises four research peptides characterized separately in the chemical literature. GHK-Cu: glycyl-L-histidyl-L-lysine coordinated to copper(II), commonly referenced under CAS 49557-75-7, with a reported ~340 g/mol mass for the 1:1 tripeptide-copper complex. BPC-157: the linear pentadecapeptide Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, PubChem CID 9941957, molecular formula C62H98N16O22, ~1419.6 g/mol, CAS 137525-51-0. TB-500: the N-acetylated heptapeptide Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln (Ac-LKKTETQ) corresponding to residues 17-23 of thymosin beta-4, PubChem CID 62707662, molecular formula C38H68N10O14, ~889.0 g/mol, CAS 885340-08-9. KPV: the tripeptide L-lysyl-L-prolyl-L-valine corresponding to the C-terminal 11-13 fragment of alpha-melanocyte-stimulating hormone, PubChem CID 125672, molecular formula C16H30N4O4, ~342.4 g/mol, CAS 67727-97-3.
Mechanism themes discussed in the literature
Each component is associated with distinct molecular-interaction themes in the research literature. GHK-Cu is studied for copper-ion coordination and tripeptide-metal complex chemistry. BPC-157 appears in studies of gastric-derived peptide stability and extracellular-matrix and cytoprotection-associated pathways. TB-500 (Ac-LKKTETQ) carries the actin-binding motif of thymosin beta-4 and is discussed in the context of cytoskeletal sequestration and cell-migration signaling. KPV, an alpha-MSH-derived tripeptide, is examined for melanocortin-pathway and inflammatory-signaling modulation in cell-based assays. The blend is intended for in-vitro investigation of these overlapping pathways within one sample.
Analytical identity and handling
Supplied as a lyophilized powder at a stated catalog strength of 80 mg total peptide content. Because KLOW Blend is a multi-component mixture, it is characterized by the identity of its individual peptides rather than by a single CAS number, molecular formula, or molecular weight; component purity is assessed by HPLC (≥98%). Recommended laboratory storage is desiccated at low temperature, protected from light and moisture, consistent with handling of multi-peptide reference standards.
Research-use-only scope
This listing describes a characterized laboratory reference material intended solely for in-vitro and analytical research. It is not a drug, cosmetic, or dietary product, and no human or veterinary application is described or implied. All references point to publicly searchable chemistry and literature databases (PubChem, PubMed) for verification of component identities.
Credible sources
- PubChem — GHK-Cu (copper tripeptide-1)
- PubChem — BPC-157 (CID 9941957)
- PubMed — thymosin beta-4 fragment / KPV peptide literature