Research Use Only — documentation confirmed by inquiry
Cagrilintide
| Units | Discount |
|---|---|
| 1–2 | 0% |
| 3–4 | 10% |
| 5–6 | 15% |
| 7–9 | 20% |
| 10–+ | 30% |
Cagrilintide (long-acting amylin-receptor agonist peptide) · ≥98% (HPLC)
Cagrilintide is a synthetic 37-residue lipidated amylin-receptor agonist peptide supplied as a characterized reference material for in-vitro receptor and analytical research. For Research Use Only. Not for human or veterinary use.
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Research context and documentation
- Why researchers study it
- Studied in receptor-pharmacology research as a long-acting amylin-analog probe engaging multiple amylin-receptor subtypes and the calcitonin receptor, often used alongside GLP-1 analogs in comparative co-agonism studies.
- Mechanism themes in research
- Amylin receptor (AMY1R/AMY2R/AMY3R) and calcitonin receptor (CTR) agonismPramlintide-backbone structure-activity substitutions (N14E, V17R, P37Y)C20 fatty-diacid lipidation enabling albumin association studied in PK/structural contextsComparative amylin/incretin co-agonism pharmacology
- What the evidence does not establish
- Published references describe research context only. They do not establish safety, efficacy, biological activity, or any outcome in humans or animals, and HELIX BioScience makes no such claims.
- Quality markers
- ≥98% (HPLC)MS contextCOA statusStorage stated where verified
- Documentation status
- Product specifications and COA status are shown on this page. Current lot documentation is provided when issued and matched to the offered lot.
Cagrilintide is a synthetic, lipidated amylin-analog peptide supplied as a characterized reference material for receptor pharmacology, peptide chemistry, and comparative amylin/incretin research. This page explains the structural and assay context without turning preclinical literature into human-use claims.
Molecular architecture
Cagrilintide is described as a 37-residue amylin analog with sequence substitutions and an N-terminal fatty-diacid modification connected through a linker. The catalog record reports an approximate molecular formula of C₁₉₄H₃₁₂N₅₄O₅₉S₂ and a molecular weight near 4409 g/mol. Because lipidated peptides can be reported with different conventions, the lot COA remains the controlling document for identity and purity.
Receptor research
Amylin analogs are studied across amylin-receptor complexes that combine calcitonin-receptor or related receptor components. Cagrilintide is therefore relevant to binding, receptor activation, second-messenger, internalization, and comparative ligand assays. Researchers should specify receptor composition and expression system: a result from one receptor complex cannot automatically be transferred to another.
| Full name | Cagrilintide (long-acting amylin-receptor agonist peptide) |
| Research theme | Metabolic signaling |
| CAS number | 1415456-99-3 |
| Molecular formula | C₁₉₄H₃₁₂N₅₄O₅₉S₂ |
| Molecular weight | 4409 g/mol |
| Purity | ≥98% (HPLC) |
| Physical form | Lyophilized powder |
| Storage | −20 °C, desiccated, protected from light |
Sequence
Reported research areas
- Amylin receptor (AMY1R/AMY2R/AMY3R) and calcitonin receptor (CTR) agonism assays
- Peptide lipidation and structure-activity studies
- Comparative amylin/incretin co-agonism pharmacology
- Analytical method development and reference standardization
Credible sources
- PubChem — Cagrilintide
- PubMed — cagrilintide amylin-receptor literature
- PubMed — amylin receptor pharmacology
COA status shown
Request the current documentation packet for the offered material. When available, it identifies the reported HPLC result and any identity method; public product specifications are not current lot results.
- HPLC result, when reported
- Identity method, when reported
- Appearance, molecular weight, and storage where documented
- Lot number and testing status
Specimen Certificate of Analysis
| Product | Cagrilintide (reference) |
| Status | Format preview — not a current lot |
| Purity (RP-HPLC) | 98%+ |
| Identity (MS) | Confirmed · 4409 g/mol |
| Appearance | Lyophilized powder |
| Storage | −20 °C, desiccated |
Format preview only. Current lot records and measured results are not published here until supplied and verified.
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