Research Use Only — documentation confirmed by inquiry
CJC-1295 / Ipamorelin (no DAC)
| Units | Discount |
|---|---|
| 1–2 | 0% |
| 3–4 | 10% |
| 5–6 | 15% |
| 7–9 | 20% |
| 10–+ | 30% |
CJC-1295 (no DAC) / Ipamorelin blend (GHRH-analog + ghrelin/GHS-R agonist secretagogue pair) · ≥98% (HPLC)
RUO reference blend pairing CJC-1295 without DAC (Mod GRF 1-29), a GHRH(1-29) analog, with Ipamorelin, a selective GHS-R peptide agonist, for in-vitro secretagogue-pathway studies.
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Characterized 44-residue GHRH-analog peptide (trans-3-hexenoyl-modified) supplied as a reference material for in-vitro receptor-signaling and analytical research. Not for human or veterinary use.
Tirzepatide
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Tirzepatide is a synthetic 39-residue lipidated dual GIP/GLP-1 receptor agonist peptide supplied as a characterized reference material for in-vitro receptor and analytical research. For Research Use Only. Not for human or veterinary use.
MOTS-c
Per-unit pricing · volume discounts at 3+ units · inquire for current availability
MOTS-c is a 16-amino-acid mitochondrial-derived peptide supplied as a characterized reference material for in-vitro mitochondrial-signaling and metabolic-pathway research. Research Use Only.
Research context and documentation
- Why researchers study it
- Studied in vitro as a paired reference material for investigating two complementary nodes of the somatotrope signaling axis — the GHRH receptor and the growth-hormone-secretagogue (ghrelin) receptor — within secretagogue-pathway and receptor-pharmacology research.
- Mechanism themes in research
- GHRH-receptor (GHRH-R) agonism — CJC-1295 without DAC as a tetrasubstituted GHRH(1-29) analogGrowth-hormone-secretagogue receptor (GHS-R1a / ghrelin receptor) agonism — Ipamorelin componentComplementary dual-pathway secretagogue signaling discussed in the literatureEnzymatic-stability modifications (D-Ala2 and additional substitutions; Aib / D-2-Nal non-natural residues) as structure-activity features
- What the evidence does not establish
- Published references describe research context only. They do not establish safety, efficacy, biological activity, or any outcome in humans or animals, and HELIX BioScience makes no such claims.
- Quality markers
- ≥98% (HPLC)MS contextCOA statusStorage stated where verified
- Documentation status
- Product specifications and COA status are shown on this page. Current lot documentation is provided when issued and matched to the offered lot.
This catalog item is a two-component research blend (catalog strength 20 mg) supplied as a lyophilized powder for Research-Use-Only applications. It pairs CJC-1295 without DAC (Mod GRF 1-29), a tetrasubstituted synthetic analog of growth-hormone-releasing hormone GHRH(1-29), with Ipamorelin, a pentapeptide selective agonist of the growth-hormone-secretagogue (ghrelin) receptor. Because it is a blend, no single CAS, molecular formula, or molecular weight applies; each component is characterized separately by sequence and analytical identity. The material is intended as a characterized reference standard for in-vitro and laboratory investigation only.
Component identity
CJC-1295 without DAC (Mod GRF 1-29) is a 29-residue GHRH(1-29) analog with substitutions at positions 2, 8, 15 and 27 (including D-Ala at position 2) reported in the literature to confer resistance to enzymatic cleavage; molecular formula C152H252N44O42 (~3367.9 g/mol). Ipamorelin is a pentapeptide, Aib-His-D-2-Nal-D-Phe-Lys-NH2 (C38H49N9O5; ~711.85 g/mol; CAS 170851-70-4; PubChem CID 9831659), incorporating the non-natural residues aminoisobutyric acid (Aib) and D-2-naphthylalanine (D-2-Nal).
Mechanism themes in the literature
The two components are described in published work as acting on distinct receptors: the CJC-1295 (no DAC) component is characterized as a GHRH-receptor (GHRH-R) agonist, while the Ipamorelin component is characterized as a selective agonist at the growth-hormone-secretagogue receptor (GHS-R1a / ghrelin receptor). The pairing is of interest as a model for studying two complementary signaling nodes of the somatotrope axis in vitro.
| Full name | CJC-1295 (no DAC) / Ipamorelin blend (GHRH-analog + ghrelin/GHS-R agonist secretagogue pair) |
| Research theme | GH secretagogue |
| CAS number | |
| Molecular formula | |
| Molecular weight | |
| Purity | ≥98% (HPLC) |
| Physical form | Lyophilized powder |
| Storage | −20 °C, desiccated, protected from light |
Sequence
Reported research areas
- Receptor pharmacology and GPCR signaling assays (GHRH-R, GHS-R1a)
- Structure-activity relationship studies of peptide secretagogue analogs
- Analytical method development and peptide characterization (HPLC / MS identity)
- In-vitro somatotrope-axis and secretagogue-pathway model systems
Credible sources
- PubChem — Ipamorelin (CID 9831659)
- PubChem search — CJC-1295 (no DAC) / Mod GRF 1-29
- PubMed — Ipamorelin and growth-hormone secretagogue receptor literature
COA status shown
Request the current documentation packet for the offered material. When available, it identifies the reported HPLC result and any identity method; public product specifications are not current lot results.
- HPLC result, when reported
- Identity method, when reported
- Appearance, molecular weight, and storage where documented
- Lot number and testing status
Specimen Certificate of Analysis
| Product | CJC-1295 / Ipamorelin (no DAC) (reference) |
| Status | Format preview — not a current lot |
| Purity (RP-HPLC) | 98%+ |
| Identity (MS) | Confirmed · |
| Appearance | Lyophilized powder |
| Storage | −20 °C, desiccated |
Format preview only. Current lot records and measured results are not published here until supplied and verified.
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