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PT-141
Melanocortin

PT-141

$45.00 per unit · 10 mg · lyophilized powder · Documentation status
Volume discounts: 3–4 units 10% off, 5–6 15%, 7–9 20%, 10+ 30%
UnitsDiscount
1–20%
3–410%
5–615%
7–920%
10–+30%

Bremelanotide (PT-141) · ≥98% (HPLC)

Cyclic melanocortin-receptor reference peptide used in MC1R/MC4R receptor-binding research.

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Full details

Research context and documentation

Why researchers study it
Studied as a cyclic melanocortin-receptor peptide in MC1R / MC4R receptor-binding research.
Mechanism themes in research
Melanocortin receptor bindingGPCR signalingNeuropeptide pharmacology
What the evidence does not establish
Published references describe research context only. They do not establish safety, efficacy, biological activity, or any outcome in humans or animals, and HELIX BioScience makes no such claims.
Quality markers
≥98% (HPLC)MS contextCOA statusStorage stated where verified
Documentation status
Product specifications and COA status are shown on this page. Current lot documentation is provided when issued and matched to the offered lot.
Documentation status Current lot documentation is available where issued. Product-specific storage and handling information follows the supplied documentation and institutional SOPs.
Research Use Only. A reference material for in-vitro laboratory research. Not for human or veterinary use. No dosing, administration, or therapeutic guidance is provided.

A cyclic melanocortin-receptor peptide used as a reference in GPCR and receptor-binding research.

What it is

Bremelanotide (PT-141) is a cyclic melanocortin-receptor peptide with formula C50H68N14O10 and an average molecular weight near 1025.2. Its cyclic architecture stabilizes the receptor-binding conformation, and it falls within the melanocortin research category.

Research and regulatory context

PT-141 has been developed and approved as a medicine in some markets. For laboratory purposes it is supplied only as a reference reagent and is widely used as a tool compound in melanocortin-receptor pharmacology research, particularly studies of MC1R and MC4R.

Full research overview →

Full nameBremelanotide (PT-141)
Research themeMelanocortin
CAS number189691-06-3
Molecular formulaC₅₀H₆₈N₁₄O₁₀
Molecular weight1025.2 g/mol
Purity≥98% (HPLC)
Physical formLyophilized powder
Storage−20 °C, desiccated, protected from light

Sequence

Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH

Reported research areas

  • Melanocortin receptor-binding assays
  • GPCR signaling studies
  • Neuropeptide pharmacology research

Credible sources

Listed research areas and sources reference published in-vitro and pre-clinical literature for scientific context only. They are not claims of efficacy and do not constitute medical, usage, or dosing guidance. Always verify against primary literature.

COA status shown

Request the current documentation packet for the offered material. When available, it identifies the reported HPLC result and any identity method; public product specifications are not current lot results.

  • HPLC result, when reported
  • Identity method, when reported
  • Appearance, molecular weight, and storage where documented
  • Lot number and testing status

View PT-141 COA library →

Specimen Certificate of Analysis

ProductPT-141 (reference)
StatusFormat preview — not a current lot
Purity (RP-HPLC)98%+
Identity (MS)Confirmed · 1025.2 g/mol
AppearanceLyophilized powder
Storage−20 °C, desiccated

Format preview only. Current lot records and measured results are not published here until supplied and verified.

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