PT-141
Bremelanotide (PT-141) · ≥98% (HPLC)
Cyclic melanocortin-receptor reference peptide used in MC1R/MC4R receptor-binding research.
- Why researchers study it
- Studied as a cyclic melanocortin-receptor peptide in MC1R / MC4R receptor-binding research.
- Mechanism themes in research
- Melanocortin receptor bindingGPCR signalingNeuropeptide pharmacology
- What the evidence does not establish
- Published references are in-vitro or pre-clinical and describe research context only. They do not establish safety, efficacy, or any outcome in humans or animals, and Helix makes no such claims.
- Quality markers
- ≥98% (HPLC)MS identityLot COACold-chain
A cyclic melanocortin-receptor peptide used as a reference in GPCR and receptor-binding research.
What it is
Bremelanotide (PT-141) is a cyclic melanocortin-receptor peptide with formula C50H68N14O10 and an average molecular weight near 1025.2. Its cyclic architecture stabilizes the receptor-binding conformation, and it falls within the melanocortin research category.
Research and regulatory context
PT-141 has been developed and approved as a medicine in some markets. For laboratory purposes it is supplied only as a reference reagent and is widely used as a tool compound in melanocortin-receptor pharmacology research, particularly studies of MC1R and MC4R.
| Full name | Bremelanotide (PT-141) |
| Research theme | Melanocortin |
| CAS number | 189691-06-3 |
| Molecular formula | C₅₀H₆₈N₁₄O₁₀ |
| Molecular weight | 1025.2 g/mol |
| Purity | ≥98% (HPLC) |
| Physical form | Lyophilized powder |
| Storage | −20 °C, desiccated, protected from light |
Sequence
Reported research areas
- Melanocortin receptor-binding assays
- GPCR signaling studies
- Neuropeptide pharmacology research
Credible sources
COA with every lot
Each PT-141 lot is characterized by reversed-phase HPLC for purity and by mass spectrometry for identity, then documented in a per-lot Certificate of Analysis. Unique lot numbers tie the vial back to its synthesis batch and analytical data.
- RP-HPLC purity result (≥98% (HPLC))
- Mass-spectrometry identity confirmation
- Appearance, molecular weight, and storage
- Lot number and testing status
Specimen Certificate of Analysis
| Product | PT-141 (reference) |
| Lot | HXR-2406-107 |
| Purity (RP-HPLC) | 98%+ |
| Identity (MS) | Confirmed · 1025.2 g/mol |
| Appearance | Lyophilized powder |
| Storage | −20 °C, desiccated |
Representative document. Each lot has its own COA — these are quality documents, not medical claims.