Research Use Only — documentation confirmed by inquiry
TB-500
| Units | Discount |
|---|---|
| 1–2 | 0% |
| 3–4 | 10% |
| 5–6 | 15% |
| 7–9 | 20% |
| 10–+ | 30% |
TB-500 (synthetic thymosin beta-4 fragment 17-23, acetylated) · ≥98% (HPLC)
TB-500 is a synthetic acetylated heptapeptide corresponding to the actin-binding active-site region of thymosin beta-4, supplied as a characterized reference material for in-vitro cell-migration and cytoskeletal research. Research Use Only.
More in Cytoprotection blend
KLOW Blend
Per-unit pricing · volume discounts at 3+ units · inquire for current availability
Multi-peptide reference blend (GHK-Cu, BPC-157, TB-500, KPV) characterized for in-vitro study of cytoprotection- and matrix-associated signaling pathways. For research use only.
BPC-157
Per-unit pricing · volume discounts at 3+ units · inquire for current availability
BPC-157 is a synthetic pentadecapeptide derived from a partial sequence of human gastric juice protein BPC, supplied as a characterized reference material for in-vitro tissue-repair and signaling research. Research Use Only.
BPC-157 / TB-500 Blend
Per-unit pricing · volume discounts at 3+ units · inquire for current availability
Two-peptide reference blend (BPC-157, TB-500) characterized for in-vitro study of overlapping tissue-repair and cytoskeletal-signaling pathways within a single analytical sample. For research use only.
Research context and documentation
- Why researchers study it
- Studied in vitro as the actin-binding active-site fragment of thymosin beta-4, isolated to investigate cytoskeletal and cell-migration signaling independent of the full-length protein's other domains.
- Mechanism themes in research
- G-actin sequestration and monomer-binding chemistryCell-migration and cytoskeletal-remodeling pathway assaysComparative structure-activity studies against full-length thymosin beta-4 (CAS 77591-33-4)Analytical reference standard for peptide identity and purity (HPLC/MS)
- What the evidence does not establish
- Published references describe research context only. They do not establish safety, efficacy, biological activity, or any outcome in humans or animals, and HELIX BioScience makes no such claims.
- Quality markers
- ≥98% (HPLC)MS contextCOA statusStorage stated where verified
- Documentation status
- Product specifications and COA status are shown on this page. Current lot documentation is provided when issued and matched to the offered lot.
An introduction to TB-500 as a Thymosin beta-4 fragment reference material used in cytoskeletal research contexts.
What it is
TB-500 is the common designation for a Thymosin beta-4 fragment, supplied as a research-use-only reference peptide. It corresponds to the actin-binding region of the parent Thymosin beta-4 protein and is catalogued under the cytoskeletal research category. Analytical identifiers include CAS number 77591-33-4 and an approximate molecular weight near 4963 g/mol.
Relationship to Thymosin beta-4
Rather than the full protein, TB-500 represents a defined sequence segment associated with actin interaction. This focus on the functional region is what makes it a useful tool compound in studies of cytoskeletal dynamics, where investigators want a tractable peptide reagent rather than the larger native molecule.
| Full name | TB-500 (synthetic thymosin beta-4 fragment 17-23, acetylated) |
| Research theme | Cytoprotection blend |
| CAS number | 885340-08-9 |
| Molecular formula | C₃₈H₆₈N₁₀O₁₄ |
| Molecular weight | 889.0 g/mol |
| Purity | ≥98% (HPLC) |
| Physical form | Lyophilized powder |
| Storage | −20 °C, desiccated, protected from light |
Sequence
Reported research areas
- Actin-sequestration and cytoskeletal-signaling assays
- Cell-migration pathway research in vitro
- Comparative structure-activity studies against full-length thymosin beta-4
- Analytical reference standard for peptide identity and purity (HPLC/MS)
Credible sources
COA status shown
Request the current documentation packet for the offered material. When available, it identifies the reported HPLC result and any identity method; public product specifications are not current lot results.
- HPLC result, when reported
- Identity method, when reported
- Appearance, molecular weight, and storage where documented
- Lot number and testing status
Specimen Certificate of Analysis
| Product | TB-500 (reference) |
| Status | Format preview — not a current lot |
| Purity (RP-HPLC) | 98%+ |
| Identity (MS) | Confirmed · 889.0 g/mol |
| Appearance | Lyophilized powder |
| Storage | −20 °C, desiccated |
Format preview only. Current lot records and measured results are not published here until supplied and verified.
Loading verified reviews…
Reviews come only from buyers we can match to a real order, and each is moderated before it appears. We never publish fabricated or incentivized reviews.