Research Use Only. Reference materials for laboratory research — not for human or veterinary use.
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Neuropeptide research · 5 articles

Semax

Semax (synthetic ACTH(4-7)-PGP heptapeptide analog) · 6 min read

An introduction to Semax, a heptapeptide ACTH(4-10) analog reference material studied in neuropeptide research.

What it is

Semax is a synthetic heptapeptide and an analog of the ACTH(4-10) sequence, supplied strictly as a research-use-only reference material. It is catalogued under the neuropeptide category and identified analytically by CAS number 80714-61-0 and a molecular weight near 813.9 g/mol with a purity specification of not less than 98% by HPLC.

Relationship to ACTH(4-10)

Semax derives from the ACTH(4-10) fragment, modified with a Pro-Gly-Pro tail at the carboxyl terminus. This terminal extension is a defining structural feature that distinguishes the analog from the native fragment and is associated with greater resistance to enzymatic breakdown in research settings.

Why it is studied

In neuropeptide research, Semax appears in studies that examine neurotrophic signaling, including connections to BDNF and NGF, as well as neuroprotection models. As a reference supplier we describe these research areas in an in-vitro and pre-clinical frame without any applied or efficacy claim.

Collection scope

The articles here cover the peptide chemistry and stability, the neuropeptide mechanisms studied in research, the analytical methods used for identity and purity, and a literature survey with search-based sources, all within a laboratory reference-material context.

Ships bench-ready

Every Semax order includes the sealed, lot-controlled vial, a measured ampoule of bacteriostatic water, and a printed handling & reconstitution card — everything to prepare the reference standard, in one box. Most suppliers ship the vial alone.

Credible sources

Research context only. This article summarizes published in-vitro and pre-clinical research for scientific context. It is not a claim of efficacy or safety and does not constitute medical, usage, or dosing guidance. HELIX BioScience products are Research Use Only and not for human or veterinary use.