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Chemistry & stability

Selank: chemistry and laboratory stability

Selank (synthetic tuftsin-analog heptapeptide) · 7 min read

The tuftsin-analog structure, solubility and storage considerations for Selank as a research standard.

Tuftsin-analog structure

Selank is a short peptide based on the tuftsin sequence and extended to enhance stability for laboratory use. Its compact, basic-residue-containing structure shapes both its solubility and its behavior during chromatographic separation, which depend on buffer pH and ionic strength.

Composition and mass

With a molecular weight near 751.9 g/mol, Selank is a small peptide whose calculated mass anchors mass-spectrometric identity work. The observed mass of a reagent lot is compared against this value to confirm the assignment during characterization.

Solubility for benchwork

As a small, water-compatible peptide, Selank is typically prepared in aqueous laboratory media for making standards and chromatography samples. Solubility guidance here applies solely to analytical sample preparation, with gentle handling to preserve the integrity of the reference material.

Stability and storage

The lyophilized solid is best stored cold, dry and protected from light to slow hydrolytic and oxidative changes. Working solutions are treated as short-lived, kept cold and protected from repeated freeze-thaw cycling. The stabilizing modifications relative to tuftsin support, but do not replace, careful custodianship.

Credible sources

Research context only. This article summarizes published in-vitro and pre-clinical research for scientific context. It is not a claim of efficacy or safety and does not constitute medical, usage, or dosing guidance. HELIX BioScience products are Research Use Only and not for human or veterinary use.